Giant Rat Disease
Disease
If the 
Target is a creature, it must succeed on a DC 10 
Fortitude or contract a disease. Until the disease is cured, the Target can't regain 
Vitalitys except by magical means, and the target's Vitality maximum decreases by 3 (1d6) every 24 hours. If the target's Vitality maximum drops to 0 as a result of this disease, the Target dies.
Persistant/Permanent Status Effect:-
Withering
d100
Mod
ADV/DIS